| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Alex Gibney | Crew | Production | Executive Producer | 6 |
 Eric Newman | Crew | Production | Executive Producer | 6 |
 Peter Berg | Crew | Directing | Director, Executive Producer | 1 |
 Noah Harpster | Crew | Production | Executive Producer | 6 |
 Micah Fitzerman-Blue | Crew | Production | Executive Producer | 6 |
Patrick Radden Keefe | Crew | Production | Executive Producer | 6 |
Keith Barnes | Crew | Crew | Driver | 1 |
 Clark Gregg | Cast | Actor | Arthur Sackler | 6 |
 Daniel Kash | Cast | Actor | Stanley | 1 |
 David Tompa | Cast | Actor | Conference Room Lawyer | 1 |
 John Ales | Cast | Actor | Dr. Gregory Fitzgibbons | 6 |
 John Rothman | Cast | Actor | Mortimer Sackler | 6 |
 Jonathan Higgins | Cast | Actor | Dr. Coyle | 1 |
 Lara Daans | Cast | Actress | Physical Therapist | 1 |
 Maria Ricossa | Cast | Actress | Else Sackler | 1 |
 Matthew Broderick | Cast | Actor | Richard Sackler | 6 |
 Neil Foster | Cast | Actor | Handyman | 1 |
 Ron Lea | Cast | Actor | Bill Havens | 6 |
 Sam Anderson | Cast | Actor | Raymond Sackler | 6 |
 Sanjay Talwar | Cast | Actor | ER Doctor | 1 |
 Simon Sinn | Cast | Actor | Focus Group Doctor #2 | 1 |
 Stuart Hughes | Cast | Actor | Tony | 2 |
 Wendy Lyon | Cast | Actress | Facilitator | 1 |
Lesley Faulkner | Cast | Actress | Elizabeth Sackler | 1 |
 Taylor Kitsch | Cast | Actor | Glen Kryger | 6 |
 Ana Cruz Kayne | Cast | Actress | Brianna Ortiz | 6 |
 David Bronfman | Cast | Actor | Focus Group Doctor #1 | 1 |
 Kyle Gatehouse | Cast | Actor | Riggs | 2 |
 Uzo Aduba | Cast | Actress | Edie Flowers | 6 |
 Carolina Bartczak | Cast | Actress | Lily Kryger | 6 |
 Dina Shihabi | Cast | Actress | Britt Hufford | 6 |
 Tyler Ritter | Cast | Actor | US Attorney John Brownlee | 6 |
 Darrin Baker | Cast | Actor | Dr. Hartman | 1 |
Cece King | Cast | Shannon's Mom | 1 | |
 Matt Baram | Cast | Actor | Dr. Robert Kaiko | 1 |
 West Duchovny | Cast | Actress | Shannon Schaeffer | 6 |
 Natasha Bromfield | Cast | Actress | Intake Nurse | 1 |
 Yasmin Lau | Cast | Actress | Hoop Earrings | 1 |
 Jack Mulhern | Cast | Actor | Tyler Kryger | 6 |
Krista White | Cast | Mary Jo White | 1 | |
 Michèle Kaye | Cast | Actress | Denise Sackler | 1 |
Dan Fox | Cast | Actor | Arthur Slacker Jr. | 1 |
Chris O'Bray | Cast | Focus Group Doctor #3 | 1 | |
 Lexie Galante | Cast | Actress | Young Rep #1 | 1 |
 Mercedes Blanche | Cast | Actress | Sorority Girl | 1 |
Catherine Tait | Cast | Jillian Sackler | 1 | |
| Person | Type | Job | Role(s) | Episodes |
