| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Alison Schapker | Crew | Production | Executive Producer, Creator | 6 |
Anna Foerster | Crew | Directing | Director, Executive Producer | 1 |
Diane Ademu-John | Crew | Production | Executive Producer, Writer, Creator | 6 |
 Frank Herbert | Crew | Writing | Novel | 6 |
 John Cameron | Crew | Production | Executive Producer | 6 |
Monica Owusu-Breen | Crew | Writing | Writer | 1 |
 Jakob Ihre | Crew | Camera | Director of Photography | 1 |
Jordan Goldberg | Crew | Production | Executive Producer, Writer | 6 |
Julie Harkin | Crew | Production | Casting | 6 |
 Scott Z. Burns | Crew | Production | Executive Producer | 6 |
 Jon Spaihts | Crew | Production | Executive Producer | 6 |
Tom Meyer | Crew | Art | Production Design | 6 |
 Volker Bertelmann | Crew | Crew | Score Engineer, Original Music Composer | 3 |
Kor Adana | Crew | Writing | Writer | 1 |
 Kevin Houlihan | Crew | Art | Art Direction | 6 |
Mike Tehrani | Crew | Sound | ADR Mixer | 6 |
 Brian Herbert | Crew | Production | Executive Producer, Novel | 6 |
Byron Merritt | Crew | Production | Executive Producer | 6 |
Kim Herbert | Crew | Production | Executive Producer | 6 |
 Kevin J. Anderson | Crew | Production | Co-Producer, Novel | 6 |
Mark Tobey | Crew | Production | Executive Producer | 6 |
Elizabeth Padden | Crew | Writing | Writer | 1 |
Silvia Mahapatra | Crew | Art | Set Designer | 6 |
Nathan Toth | Crew | Production | Casting | 6 |
Matthew King | Crew | Production | Executive Producer | 6 |
 Emily Watson | Cast | Actress | Mother Superior Valya Harkonnen | 6 |
 Jodhi May | Cast | Actress | Empress Natalya | 3 |
 Mark Strong | Cast | Actor | Emperor Javicco Corrino | 6 |
 Olivia Williams | Cast | Actress | Tula Harkonnen | 3 |
 Tabu | Cast | Actress | Sister Francesca | 6 |
 Travis Fimmel | Cast | Actor | Desmond Hart | 6 |
 Chris Mason | Cast | Actor | Keiran Atreides | 6 |
 Jade Anouka | Cast | Actress | Sister Theodosia | 6 |
 Sarah-Sofie Boussnina | Cast | Actress | Princess Ynez Corrino | 6 |
 Shalom Brune-Franklin | Cast | Actress | Mikaela | 6 |
 Aoife Hinds | Cast | Actress | Sister Emeline | 6 |
 Edward Davis | Cast | Harrow Harkonnen | 6 | |
 Yerin Ha | Cast | Actress | Young Kasha | 6 |
 Chloe Lea | Cast | Lila | 3 | |
 Josh Heuston | Cast | Actor | Constantine | 3 |
 Faoileann Cunningham | Cast | Actress | Sister Jen | 6 |
| Person | Type | Job | Role(s) | Episodes |
