| Person | Type | Job | Role(s) |
|---|---|---|---|
 Anthony Hinds | Crew | Production | Producer |
Anthony Nelson Keys | Crew | Production | Production Supervisor |
 Bernard Robinson | Crew | Art | Art Direction |
Don Weeks | Crew | Directing | Assistant Director |
Gerald Gibbs | Crew | Camera | Director of Photography |
James Bernard | Crew | Sound | Original Music Composer |
James Needs | Crew | Editing | Editor |
 Michael Carreras | Crew | Production | Executive Producer |
 Nigel Kneale | Crew | Writing | Screenplay, Teleplay |
Philip Leakey | Crew | Costume & Make-Up | Makeup Artist |
 Val Guest | Crew | Writing | Screenplay, Director |
Bill Warrington | Crew | Crew | Special Effects |
John Workman | Crew | Production | Production Manager |
John Hollingsworth | Crew | Sound | Music Director |
Frank George | Crew | Crew | Special Effects |
Rene Coke | Crew | Costume & Make-Up | Wardrobe Supervisor |
Henry Harris | Crew | Crew | Special Effects |
 Barry Lowe | Cast | Actor | Chris (uncredited) |
 Brian Donlevy | Cast | Actor | Prof. Bernard Quatermass |
 Bryan Forbes | Cast | Actor | Marsh |
 Charles Lloyd Pack | Cast | Actor | Work Camp Manager Dawson |
 Edwin Richfield | Cast | Actor | Peterson |
 George Merritt | Cast | Actor | Super |
Jane Aird | Cast | Mrs. McLeod | |
 John Fabian | Cast | Actor | Intern |
 John Longden | Cast | Actor | Chief Inspector Lomax |
John Rae | Cast | Actor | E. J. Macleod |
 John Stuart | Cast | Actor | The Police Commissioner |
 John Van Eyssen | Cast | Actor | The Plant Tour Guide |
 Marianne Stone | Cast | Actress | Miss Beal |
 Michael Balfour | Cast | Actor | Harry |
 Michael Ripper | Cast | Actor | Ernie the Bartender |
 Percy Herbert | Cast | Actor | Paddy Gorman |
 Sid James | Cast | Actor | Jimmy Hall |
Tom Chatto | Cast | Actor | Vincent Broadhead, M.P. |
 Vera Day | Cast | Actress | Sheila |
 William Franklyn | Cast | Actor | Dr. Tom Brand |
Betty Impey | Cast | Actress | Kelly |
Philipp Baird | Cast | Lab Assistant | |
Joyce Adams | Cast | Woman Member of Parliament | |
| Person | Type | Job | Role(s) |
